Question : Working with MDE files on Citrix PS 4.5

In the past we have set up a separate folder for each employee with MDE files in each folder. They are the exact same MDE's just copied into each folder, that way each person has their own set of MDE files. Updating these files as well as setting up new users has become a real hassle. Can anyone tell me a better way to do this? I have heard about publishing in isolation but I'm not sure how to do this or if it will even solve my problem as I have some users that are logging onto the Citrix Desktop. Half of our users have been using published apps while the other half have Citrix desktop access so I need to have both working with their own set of MDE's. We have PS 4.5 with the XenApp 5.0 update on there, the rollup pack, as well as all hotfixes. Thanks in advance!

Answer : Working with MDE files on Citrix PS 4.5

You also asked about Isolation Environments:

Here is an article that explains installation of applications in isolation environment:
http://support.citrix.com/article/CTX112758

And some conceptual ones on the topic:
http://www.brianmadden.com/blogs/guestbloggers/archive/2005/05/12/understanding-application-isolation-environments-aie-in-citrix-presentation-server-4.aspx

http://www.brianmadden.com/blogs/brianmadden/archive/2006/04/27/limitations-of-citrix-s-application-isolation-environments.aspx