Couldn't find the article for some reason, but here it is now:
http://support.microsoft.com/kb/822179/en-usQuoting:
"You can run Exchange Server 2003 on either a member server or on a domain controller. After you install Exchange Server 2003 on a server, do not change the role of the server. For example, if you install Exchange Server 2003 on a member server, do not use the Dcpromo tool to promote the server to a domain controller. Or, if you install Exchange Server 2003 on a domain controller, do not use the Dcpromo tool to demote the server to a member server. Changing the role of a server after you install Exchange Server 2003 may result in loss of some Exchange functionality and is not supported."
Chris